Geographic differences in EpiPen scripts
BOSTON, July 16 A study suggests strong variation in the occurrence of anaphylaxis between the northern and southern United States because of EpiPen prescribing.
Anaphylaxis is a severe allergic reaction that can be fatal without treatment with epinephrine, according to Dr. Carlos A. Camargo of Harvard University, and colleagues who obtained data on EpiPen prescriptions in 2004 for all 50 states and Washington.
They used state populations to calculate the average number of prescriptions written per person and found the highest number of prescriptions per 1,000 persons was in Massachusetts with 11.8. Hawaii had the lowest with 2.7 prescriptions per 1,000 persons.
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On average, there were 5.71 EpiPens prescribed per 1000 persons in the United States, according to the Journal of Allergy and Clinical Immunology.
New England had the highest values with eight to 12 EpiPen prescriptions per 1000 persons, while southern states had three prescriptions per 1000 persons.
The study authors suggest that perhaps more year-round sunshine in the south led to higher Vitamin D levels and could explain the north-south difference in the incidence of respiratory and allergic disease.